About the Registry
The International Society for Heart and Lung Transplantation Registry for Mechanically Assisted Circulatory Support (IMACS) is an international registry intended to enroll and follow patients who receive durable mechanically assisted circulatory support devices (MCSD) in all countries and hospitals that wish to participate. Durable devices are defined as those devices that are capable of allowing patient discharge with the device in place. Devices are defined on a country by country basis. The registry will record pre-implant patient information, device information and will track the major post implant clinical events.
The primary goal of the IMACS Registry is to create, implement and analyze a registry that contains high standards for complete enrollment of patients and complete and accurate submission of MCSD data that allows participating centers to engage in important outcomes research about mechanical support devices.
ISHLT has awarded a three year contract to the Division of Cardiothoracic Surgery at the University of Alabama at Birmingham (UAB) under the direction of Dr. James K. Kirklin. UAB will serve as the data coordinating and analysis center (DCAC). The programming for the web-based data entry system will be performed by the Transplant Informatics Institute (TII), in Richmond, Virginia under a subcontract to UAB. TII is a subsidiary of the United Network for Organ Sharing (UNOS), which is the contractor for the United States Government’s Organ Procurement and Transplantation Network.
The specific mission of IMACS is the promotion of scientific investigations and publications based on analyses of this multinational database, providing the opportunity for an international array of authors to collaborate in Registry investigations, presentations, and publications.
- To capture worldwide data relating to the implantation and outcome of patients receiving cardiac assist devices designed for and capable of use for 30 or more days
- To identify risk factors for complications
- To improve patient selection and management before and after device implantation
- To generate predictive models of outcome for given patient profiles
- To generate statistical analyses of the data that can be used as the underlying evidence/ justification for government agency funded studies and clinical trials
- To identify overall and best practices with the aim of improving current practices
WHY PARTICIPATE IN IMACS?
Benefits to Centers
Benefits to ISHLT
- Statistical summaries of hospital experience
- Benchmarks for comparison against the international experience
- Description of performance standards for units and practitioners
- Determine resources (personnel, skills, training) needed to meet performance standards
- Participate in device research
- Generate volume and trend data to facilitate short and long term financial planning
Benefits to MCS Community
- Own and direct an international high quality MCSD registry
- Complement the ISHLT transplant registry as ISHLT emphasizes its role in MCSD research
- Provides Statistical Reports and Research Analyses to ISHLT Researchers
- Improved outcomes from new techniques and devices
- Facilitate accelerated evaluation of new devices
- Development of international standards for MCS therapy